[Vp-integration-subgroup] [Vp-reproduce-subgroup] Shayn Peirce-Cottler via Frontiers: Manuscript

Torres, Marcella mtorres at richmond.edu
Wed Jan 26 15:12:01 PST 2022


Email from Frontiers and question from the editor shared below:

Dear Dr Torres,

Frontiers in Systems Biology Editorial Office has sent you a message. Please click 'Reply' to send a direct response

New comments were posted by Specialty Chief Editor Shayn Peirce-Cottler. Please visit the review forum using the link below and address these comments within the coming week:
http://www.frontiersin.org/Review/EnterReviewForum.aspx?activationno=ba15539e-1784-4ed3-9969-2aacb1b5b835<http://links.email.frontiersin.org/ls/click?upn=99YMbkkQ8WNJiHLectmHSn5XnTmYe57aPeiziTpYNtyfClFbQqFlwPq2nUMZBzQ7srQvkLkPbc-2F-2BZbZ-2BczlOsPrTMbzmmMktcODsIp2h-2Ffj90r8fRFX2WoaacyAq0r1DpdlwAI9E7tBq-2Fy-2F2Oci2ve-2FCfkFNdVsmiG1bos-2FvnrU-3DZcy-_B-2Fy9jbSVGoT8qhSwbw0AFtm6DlDsGMQJjIadnFC13-2FJyATqJzBD73VYfuDTc-2F-2BJaJPaJJ5oSKrMDAr6Ompo1c21QYWQoQgYfAYNEjVnB244sSGd8-2BEkyma7zMD5B9L6sx2V7r1JTwJYDZpx5bqIUznnbkYmAKXcibTaFF47hgopNpnsrFZkqBi6O6g8b4EiWw24vVRZnhel591eZQKRdrLT3faq2B-2F0DXCpdcIRO-2FjNMfVBXwcpPniAJnsg8Tlmf>

Journal: Frontiers in Systems Biology, section Multiscale Mechanistic Modeling
Article type: Review
Manuscript title: Model Integration in Computational Biology: the Role of Reproducibility, Credibility and Utility
Manuscript ID: 822606
Authors: Jonathan Karr, Rahuman S. Malik Sheriff, James Osborne, Gilberto Gonzalez Parra, Eric Forgoston, Ruth Bowness, Yaling Liu, Robin Thompson, Winston Garira, Jacob Barhak, John Rice, Marcella Torres, Hana Maria Dobrovolny, Tingting Tang, William Waites, James Glazier, James Faeder, Alexander Kulesza
Submitted on: 26 Nov 2021
Edited by: Shayn Peirce-Cottler


Research Topic: Insights in Systems Biology: Multiscale Mechanistic Modeling 2021

Best regards,

Your Frontiers in Systems Biology team

Frontiers in Systems Biology Editorial Office
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For technical issues, please contact our IT Helpdesk - support at frontiersin.org
?[cid:4d9f5d6e-a6f6-40ed-9e3e-c15bb1e27459]
Marcella Torres, Ph.D.
Director of Mathematical Studies
University of Richmond
Jepson Hall Room 212
221 Richmond Way
Richmond, VA 23173
(804) 289-8081
Pronouns:  she/her

________________________________
From: Vp-reproduce-subgroup <vp-reproduce-subgroup-bounces at lists.simtk.org> on behalf of Jacob Barhak <jacob.barhak at gmail.com>
Sent: Wednesday, January 19, 2022 10:24 PM
To: James Glazier <jaglazier at gmail.com>
Cc: vp-reproduce-subgroup at lists.simtk.org <vp-reproduce-subgroup at lists.simtk.org>; vp-integration-subgroup at lists.simtk.org <vp-integration-subgroup at lists.simtk.org>
Subject: Re: [Vp-reproduce-subgroup] [Vp-integration-subgroup] Shayn Peirce-Cottler via Frontiers: Manuscript

External Email: Use caution in opening links, attachments, and buying gift cards.



Hi James,


Here is the text I added to the submission system to correct your name and draw the attention of the editor to the funding issue we discussed.


Hopefully no other changes will be raised by contributors and we can proceed as approved by all authors.


             Jacob



####### Letter to the editor sent in submission system  ########



Another author asked to change their name - adding a middle initial. I cannot do those changes in the manuscript myself through the system since it does not allow making those changes. Here is the proper name with the proper middle initial:

James A. Glazier



Also, I am making a round of checks that all funding sources and conflict of interests have been submitted properly.  Here is the link to the public communications:

https://lists.simtk.org/pipermail/vp-integration-subgroup/2022-January/000388.html

Hopefully no other changes are necessary.



Thank you for handling this manuscript.



                    Jacob



On Wed, Jan 19, 2022 at 9:05 PM Jacob Barhak <jacob.barhak at gmail.com<mailto:jacob.barhak at gmail.com>> wrote:
Thanks James, and all other paper contributors, please read this.

Your email clarifies things. We did agree long ago that funding sources are at the discretion of the contributor although this was a volunteer effort. A few insisted on adding their funding source and we did add those. Here is some the discussion that we held:
https://lists.simtk.org/pipermail/vp-integration-subgroup/2021-April/000073.html

Sheriff's request came in late and should not have been submitted that late in the process, yet I decided to include his funding source because it has legal implications if it is not included - I assume that tax payer money paid for the time he spend on this manuscript and this requires traceability - I was surprised with his declaration that does not include a traceable source of fund yet to avoid any wrongdoing I decided to include it. I made the email public so that everyone knows and can reciprocate.

In the manuscript submission form there is a clause about declaration of funding. When I signed it, I knew I was accurate in my statement about how this work was funded. It is important that these declarations are correct since many times taxpayer money funds this work and that money needs to be traceable for accounting reasons and to avoid misuse of funds. There are legal implications to incorrect declarations on this question. As far as I knew, except from very few that declared funding early on when we discussed it, this was a volunteer group. And for those who did declare I assumed this was to trace public funds.

I am sending this email to the entire group to make sure that everyone that approved, knew that they are approving the paper text, the funding sources, the conflict of interest statements, the authorship / ethics statement., license and more elements as declared in this document: https://www.frontiersin.org/about/policies-and-publication-ethics

If anything was lost through communications I am raising again now so everyone will know what they are signed on. I want to make sure that when I signed in your name I was not misrepresenting anything.

So if anyone who reads this, and after my explanation believes that they need to correct a funding statement, a conflict of interest statement, or any other detail regarding the manuscript that has legal implications, please announce it NOW and quickly so changes will be made prior to publication. After publication, such changes may be very complicated and have other implications.

In simpler words, if your time spent on handling this paper was funded by the taxpayer or by an entity that requires reporting the funding source, you MUST declare it. If you volunteered your own time for this paper, you just have to make sure you have no other conflict.

Hopefully I am clear enough now.

I will write to the editor about adding the middle initial in your name - I can no longer do this though the submission system - it blocked me changing the authors - this is why I wrote to the editor about the request from William Waites to add his second affiliation.

I am not sure if there are any more proof stages where we can fix things - the publication process is different from venue to venue and it's important we will be accurate in declarations.

Hopefully this email will fix things and make sure our delerations are accurate.


                     Jacob




On Wed, Jan 19, 2022 at 12:31 PM James Glazier <jaglazier at gmail.com<mailto:jaglazier at gmail.com>> wrote:
Dear Jacob:

I sent the minor corrections I did because I saw your response to Rahuman. I had not thought initially that you were listing funding sources, but your response to Rahuman suggested you were. So if you don't want to list funding, it's ok with me. I would prefer to have the middle initial added if possible, simply because I otherwise get confused with a different James Glazier, but it isn't critical.

JAG

On Wed, Jan 19, 2022 at 1:22 PM Jacob Barhak <jacob.barhak at gmail.com<mailto:jacob.barhak at gmail.com>> wrote:
Well James,

You put me is a difficult position. You all approved the manuscript multiple times.

Sheriff caught it just before I sent it  so I added his funding - out of regular process -  just to avoid conflict with journal legal requirements.

As for name changes, I am locked outside the system and such a request should be processed through the editor. Similar to what William asked for.

As for funding. We discussed this a long time ago. And the paper was approved multiple times.  I can probably spend an hour later to add your funding. Yet there are 18 of us and only a few claimed funding - this was supposed to be a volunteer effort... If all 18 ask their funding to be included, we will need to reopen this again.

So I ask you on what should I do.

If this funding declaration is necessary for this volunteer work to fulfill the legal requirement of the publisher to disclose funding I must process your request and will do it tonight. If not , I suggest we avoid changes. Please advise on proper way to proceed.

Hopefully this will settle the matter.

         Jacob


On Wed, Jan 19, 2022, 11:15 James A Glazier <jaglazier at gmail.com<mailto:jaglazier at gmail.com>> wrote:

Dear Jacob:

Thank you for your heroic efforts on bringing this paper together. I should probably change my name to James A. Glazier, which is my standard listing. I should also acknowledge my funding support:

James A. Glazier acknowledges funding support from grants NSF 188553, NSF 186890, NSF 1720625, NIH U24 EB028887 and NIH R01 GM122424.

JAG


On 11/17/2021 10:04 PM, Jacob Barhak wrote:
Hi James Faedar, Hi John Rice,

Please check the manuscript and declare by REPLY ALL if you APPROVE, DISAPPROVE or ABSTAIN.

James, if you responded and I did not get the email, I apologize - there are some communication hiccups occasionally. Yet I need your public approval to proceed and use your name.

John, I know you allowed us to send the paper, yet you need to be specific and declare if you want to be included as an Author or just moved to acknowledgements. You did have a major contribution, so I hope you will APPROVE.

Once I have your answer I can proceed. Hopefully you will both APPROVE quickly.

               Jacob

On Wed, Nov 17, 2021 at 3:02 PM sheriff <sheriff at ebi.ac.uk<mailto:sheriff at ebi.ac.uk>> wrote:

Hi Jacob and all,

I approve the submission of the manuscript.

Please update the citation Tiwari et 2020 Preprint to

Tiwari K, Kananathan S, Roberts MG, Meyer JP, Sharif Shohan MU, Xavier A, Maire M, Zyoud A, Men J, Ng S, Nguyen TVN, Glont M, Hermjakob H, Malik-Sheriff RS. Reproducibility in systems biology modelling. Mol Syst Biol. 2021 Feb;17(2):e9982. doi: 10.15252/msb.20209982. PMID: 33620773; PMCID: PMC7901289.

Also my name and affiliation below

Rahuman S. Malik Sheriff

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK


Thanks for pushing this work forward

Best regards

Sheriff


On 2021-11-17 18:58, Jonathan Karr wrote:

Hi Jacob,

Thank you again for spearheading this effort.

I approve the submission. I think the paper organizes a variety of important issues toward more credible models, and the content is sound.

My affiliation is Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

As others have mentioned, I think the paper would be more impactful with further editing to make the paper easier to read:

  *   More clearly articulate the goals/motivation for more credible models
  *   Be more concise and focused
  *   Remove redundancies by grouping related text
  *   Fill in the gaps in logic in the introduction with more transitions, less extraneous information, and/or a brief outline.
  *   Change the title of the "Utility of models" section to something like "Challenges with using multiscale models" (James' suggestion)
  *   Order the "Utility of models" subsections to be easier to follow, perhaps from model construction through to reuse
  *   Rephrase the titles of the  "Utility of models" subsections to focus on opportunities for improvement rather than current problems

Regards,
Jonathan

On Wed, Nov 10, 2021 at 11:25 PM Jacob Barhak <jacob.barhak at gmail.com<mailto:jacob.barhak at gmail.com>> wrote:
Thanks to all contributors who answered,

Most contributors approved by now.

James and Wiliam, I am not sure how many more revisions there will be for this publication. I did not add several important references of my own in this revision. Frankly I wanted to keep reference changes to a minimum and kept it as close as possible to the origin . However, we are transferring the paper to the publisher under CC license, so it will not be hard to create another derived version with all sorts of additions and modifications in the future where people can edit it as they see fit and add whatever references they want - so after it gets published you can continue working on other versions as you see fit. For now I ask we focus on publishing this version alone and I really hope the editors will not put us through another revision round since it makes no sense at this point - any change is not substantial compared to what we have already and any delay is more damaging than productive.

To be productive I ask that the following people who did not answer so far take the time to APPROVE, DISAPPROVE, or ABSTAIN.:
Robin Thompson
James R. Faeder
Jonathan Karr
Rahuman Sheriff
John Rice

John Rice - thanks for your support, yet you will have to be specific: You can either choose APPROVE or ABSTAIN - both of these options will move the paper forwards. APPROVE will add your name to the list of authors with all responsibilities and privileges listed or implied , ABSTAIN will put you in acknowledgements without any obligation. So John, please choose if you want your name on the paper or not in this specific version - any decision you make will be ok.

I hope we can father all support quickly so I can move forward and submit the paper.

                      Jacob


On Tue, Nov 9, 2021 at 5:46 AM William Waites <wwaites at ieee.org<mailto:wwaites at ieee.org>> wrote:
I'm just chasing down references for use in another context and I notice that the Ke et al paper is still a pre-print after more than a year. There is no problem in my opinion citing preprints but it is suspect in this case: there's been a ton of work on SARS-CoV-2 infectiousness, why didn't this get published? Probably not best to rely on it as an example of practice. Perhaps to fix on revision.

-w

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--
James A. Glazier, PhD
Professor of Intelligent Systems Engineering, Adjunct Professor of Physics
Director, Biocomplexity Institute
Indiana University, Bloomington
(812) 391-2159 (cell)


--
James A. Glazier, PhD
Professor of Intelligent Systems Engineering, Adjunct Professor of Physics
Director Biocomplexity Institute
Indiana University, Bloomington
(812) 391-2159
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