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<span style="font-size:12.0pt;font-family:"Arial","sans-serif";mso-fareast-font-family:"Times New Roman";color:black;mso-bidi-font-weight:bold">I could not attend the zoom meeting because there was another meeting with graduate students at<span style="mso-spacerun:yes">
</span>the same time.<span style="mso-spacerun:yes"> </span>I have read through the interesting communications that have been ongoing since yesterday from the subgroup. I will be able to contribute and edit challenge 9:
<span style="mso-spacerun:yes"> </span>"Environments to adapt and integrate models</span><span style="font-size:12.0pt;font-family:"Arial","sans-serif";mso-fareast-font-family:"Times New Roman";color:black">". Already an interesting discussion has been initiated
in the form of <span style="mso-spacerun:yes"> </span>the following statements:<o:p> </o:p></span></p>
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<span style="font-size:12.0pt;font-family:"Arial","sans-serif";color:#984807;mso-themecolor:accent6;mso-themeshade:128;mso-style-textfill-fill-color:#984807;mso-style-textfill-fill-themecolor:accent6;mso-style-textfill-fill-alpha:100.0%;mso-style-textfill-fill-colortransforms:lumm=50000">>If
you separately accredit M1 and M2 for your purpose, and they fit together like lego, it does not >automatically mean that M1 + M2 is credible. One of the things we would like to know is, what >properties must M1 and M2 have for us to safely believe that we
understand what M1 + M2 does. We >only know this for a few special cases today.<o:p> </o:p></span></p>
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<span style="font-size:12.0pt;font-family:"Arial","sans-serif";mso-fareast-font-family:"Times New Roman";color:black">Two issues need consideration here. If M1and M2 are different models describing phenomena at the same scale, then perhaps this is the few special
cases where we may know that <span style="mso-spacerun:yes"> </span>M1+M2 is credible. This is because “+” is much easier to define in that case. However, if M1 and M2 describe phenomena at different scales then
<span style="mso-spacerun:yes"> </span>the problem of<span style="mso-spacerun:yes">
</span>defining <span style="mso-spacerun:yes"> </span>“+” becomes even more challenging. Defining “+” involves defining methods for
<span style="mso-spacerun:yes"> </span></span><span style="font-size:12.0pt;font-family:"Arial","sans-serif"">linking/coupling/integrating<span style="mso-spacerun:yes">
</span>models from the different <span style="mso-spacerun:yes"> </span>scales</span><span style="font-size:12.0pt;font-family:"Arial","sans-serif";mso-fareast-font-family:"Times New Roman";color:black">.<span style="mso-spacerun:yes">
</span></span><span style="font-size:12.0pt;font-family:"Arial","sans-serif";color:black">For
<span style="mso-spacerun:yes"> </span>multiscale modelling, the different <span style="mso-spacerun:yes">
</span>scales <span style="mso-spacerun:yes"> </span>indicate/represent shifts/changes/transitions in
<span style="mso-spacerun:yes"> </span>processes for the complex system under consideration and we
</span><span style="font-size:12.0pt;font-family:"Arial","sans-serif"">do not know in general how scale transition occurs<span style="color:black">. For example in infectious disease dynamics there is usually
<span style="mso-spacerun:yes"> </span>pathogen replication at the microscale scale and pathogen
<span style="mso-spacerun:yes"> </span>transmission at the macroscale [1].<span style="mso-spacerun:yes">
</span></span></span><span style="font-size:12.0pt;font-family:"Arial","sans-serif";mso-fareast-font-family:"Times New Roman";color:black">There is no single unique and widely acceptable method/way of defining “+” or integrating models for a given M1 and M2.
<span style="mso-spacerun:yes"> </span>In the past, I have considered the different ways in which to define “+”<span style="mso-spacerun:yes">
</span>when M1 and M2 describe infectious disease phenomena at different scales (i.e the microscale and macroscale). This enabled me to come up with 5 different categories of multiscale<span style="mso-spacerun:yes">
</span>models of disease dynamics [2,3]. <span style="mso-spacerun:yes"> </span></span><span style="font-size:12.0pt;font-family:"Arial","sans-serif"">So even
<span style="color:black;mso-themecolor:text1">if<span style="mso-spacerun:yes">
</span>M1 and M2 <span style="mso-spacerun:yes"> </span>have the correct properties we may not safely
<span style="mso-spacerun:yes"> </span>believe what M1 + M2 does because there is still an additional challenge of identifying the correct
</span></span><span style="font-size:12.0pt;font-family:"Arial","sans-serif";mso-fareast-font-family:"Times New Roman";color:black;mso-themecolor:text1">“+”</span><span style="font-size:12.0pt;font-family:"Arial","sans-serif";color:black;mso-themecolor:text1">
which turns out to be the greatest challenge in multiscale modelling.<o:p> </o:p></span></p>
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<span style="font-size:12.0pt;font-family:"Arial","sans-serif""><o:p> </o:p></span></p>
<p class="Default" style="margin:0in 0in 0.0001pt;font-size:12pt;font-family:"Arial", "sans-serif";color:black;text-align:justify">
[1.] Garira, W. (2019). The Replication-Transmission Relativity theory for Multiscale Modelling of infectious Disease Systems. Scientific reports, 9(1), 1-17.
<o:p> </o:p></p>
<p class="MsoNormalCxSpFirst" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Arial","sans-serif"">[2.] Garira, W. (2017). A complete categorization of multiscale models of infectious disease systems. Journal of biological dynamics, 11(1),
378-435.<o:p> </o:p></span></p>
<p class="MsoNormalCxSpLast" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Arial","sans-serif"">[3.] Garira, W. (2018). A primer on multiscale modelling of infectious disease systems. Infectious Disease Modelling, 3, 176-191.
<o:p> </o:p></span></p>
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<b><span style="mso-bidi-font-size:12.0pt;font-family:"Arial","sans-serif";mso-no-proof:yes">Winston Garira, PhD<o:p> </o:p></span></b></p>
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<b><span style="mso-bidi-font-size:12.0pt;font-family:"Arial","sans-serif";mso-no-proof:yes">DEPARTMENT OF MATHEMATICS AND APPLIED MATHEMATICS<o:p> </o:p></span></b></p>
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<b><span style="mso-bidi-font-size:12.0pt;font-family:"Arial","sans-serif";mso-no-proof:yes">Modelling Health and Environmental Linkages Research Group (MHELRG)<o:p> </o:p></span></b></p>
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<b><span style="mso-bidi-font-size:12.0pt;font-family:"Arial","sans-serif";mso-no-proof:yes">University of Venda, Private Bag X5050, Thohoyandou 0950, South Africa.
<o:p><br>
</o:p></span></b></p>
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<b><span style="mso-bidi-font-size:12.0pt;font-family:"Arial","sans-serif";mso-no-proof:yes">Email(1):
<u><span style="color:blue"><a href="mailto:winston.garira@univen.ac.za">winston.garira@univen.ac.za</a></span></u>, Email(2):
<u><span style="color:blue"><a href="mailto:wgarira@gmail.com">wgarira@gmail.com</a></span></u></span></b><span style="mso-bidi-font-size:12.0pt;font-family:"Arial","sans-serif";mso-no-proof:yes"><o:p> </o:p></span></p>
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<div id="divRplyFwdMsg" dir="ltr"><font face="Calibri, sans-serif" style="font-size:11pt" color="#000000"><b>From:</b> Jacob Barhak <jacob.barhak@gmail.com><br>
<b>Sent:</b> Tuesday, 18 May 2021 17:17<br>
<b>To:</b> William Waites <wwaites@ieee.org><br>
<b>Cc:</b> Tomas Helikar <thelikar2@unl.edu>; vp-reproduce-subgroup@lists.simtk.org <vp-reproduce-subgroup@lists.simtk.org>; vp-integration-subgroup@lists.simtk.org <vp-integration-subgroup@lists.simtk.org>; Winston Garira <Winston.Garira@univen.ac.za>; Faeder,
James R <faeder@pitt.edu><br>
<b>Subject:</b> Re: [Vp-integration-subgroup] [EXT] Re: White paper revision</font>
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<div dir="ltr">So William,
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<div>For now, you should just claim the sections you wish to edit - I think your name is mentioned already, yet check out the rest of the sections. This will give John a picture of who he has to satisfy when he makes edits. </div>
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<div>Once he has a full picture we can start actual editing. He will decide where edits go - I suggested using the existing version so changes are reflected in one location and we will have a traceable track of changes - if he prefers another link it's fine
- yet I asked him to secure the document and provide links to older versions the document is derived from. It is after all a paper about reproducibility. And I did experience security issues in the past in collaborative work that needed treatment, so this
is why I asked for those. You really do not want an anonymous animal using your public document as it sees fit - remember that our conversations are public as well as the links. </div>
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<div>He promised 2 weeks and I do not envy him if he has to go through the history of contributions and locate authors who contributed to each section, this is why we are declaring what sections are are interested in - Sheriff suggested this yesterday. So please
just look at the sections John mentioned with his numbering and declare what you want to edit. Once we all claimed sections, John can more easily decide what to edit and how without facing potential objections. </div>
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<div>I hope this makes sense now and you know your next move.</div>
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<div> Jacob</div>
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<div dir="ltr" class="x_gmail_attr">On Tue, May 18, 2021 at 9:57 AM William Waites <<a href="mailto:wwaites@ieee.org">wwaites@ieee.org</a>> wrote:<br>
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> On 18 May 2021, at 15:30, Tomas Helikar <<a href="mailto:thelikar2@unl.edu" target="_blank">thelikar2@unl.edu</a>> wrote:<br>
> <br>
> Since John is taking the lead on the new version, my suggestion is to let him do it the way that will be most efficient for him. I think everyone, including John, have noted your concerns.<br>
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I agree. But I am also now completely confused about which document it is ok for who to edit when.<br>
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-w<br>
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