<html>
  <head>
    <meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
  </head>
  <body>
    <p>Dear Jacob:</p>
    <p>I approve. Please go ahead and submit. There is a huge amount of
      effort represented in the manuscript. I expect that referees may
      ask for some reworking and cleanup to improve coherence, but I am
      happy with you to submit it. Veronika and I did a short review on
      the role of modeling in viral therapies: Zarnitsyna, Veronika I.,
      Juliano Ferrari Gianlupi, Amit Hagar, T. J. Sego, and James A.
      Glazier. "Advancing therapies for viral infections using
      mechanistic computational models of the dynamic interplay between
      the virus and host immune response." Current Opinion in Virology
      50 (2021): 103-109. which you might add on revision.</p>
    <p>Thank you for your heroic efforts.</p>
    <p>JAG<br>
    </p>
    <p><br>
    </p>
    <div class="moz-cite-prefix">On 11/7/2021 3:12 PM, Yaling Liu wrote:<br>
    </div>
    <blockquote type="cite"
cite="mid:CAJsuQ_hynE90npWTaBZ+8iyiqVz6kGnCa9M1XLqY=QpcObXVuQ@mail.gmail.com">
      <meta http-equiv="content-type" content="text/html; charset=UTF-8">
      <div dir="ltr">
        <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)">Dear
          Jacob,</div>
        <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)"><br>
        </div>
        <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)">I
          approve the paper for submission.</div>
        <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)"><br>
        </div>
        <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)">Thanks.</div>
        <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)"><br>
        </div>
        <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)">Yaling</div>
      </div>
      <br>
      <div class="gmail_quote">
        <div dir="ltr" class="gmail_attr">On Sun, Nov 7, 2021 at 9:59 AM
          Winston Garira <<a
            href="mailto:Winston.Garira@univen.ac.za"
            moz-do-not-send="true" class="moz-txt-link-freetext">Winston.Garira@univen.ac.za</a>>
          wrote:<br>
        </div>
        <blockquote class="gmail_quote" style="margin:0px 0px 0px
          0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex">
          <div dir="ltr">
            <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)">Dear
              Jacob,</div>
            <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)"><br>
            </div>
            <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)">I
              approve the paper for submission.</div>
            <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)"><br>
            </div>
            <div
style="font-family:Calibri,Arial,Helvetica,sans-serif;font-size:12pt;color:rgb(0,0,0)">Winston<br>
            </div>
            <hr style="display:inline-block;width:98%">
            <div id="gmail-m_-5943549780352006519divRplyFwdMsg"
              dir="ltr"><font style="font-size:11pt" face="Calibri,
                sans-serif" color="#000000"><b>From:</b> William Waites
                <<a href="mailto:wwaites@ieee.org" target="_blank"
                  moz-do-not-send="true" class="moz-txt-link-freetext">wwaites@ieee.org</a>><br>
                <b>Sent:</b> Sunday, 07 November 2021 12:34<br>
                <b>To:</b> Jacob Barhak <<a
                  href="mailto:jacob.barhak@gmail.com" target="_blank"
                  moz-do-not-send="true" class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>><br>
                <b>Cc:</b> James Osborne <<a
                  href="mailto:jmosborne@unimelb.edu.au" target="_blank"
                  moz-do-not-send="true" class="moz-txt-link-freetext">jmosborne@unimelb.edu.au</a>>;
                <a href="mailto:vp-reproduce-subgroup@lists.simtk.org"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">vp-reproduce-subgroup@lists.simtk.org</a>
                <<a
                  href="mailto:vp-reproduce-subgroup@lists.simtk.org"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">vp-reproduce-subgroup@lists.simtk.org</a>>;
                James A Glazier <<a href="mailto:jaglazier@gmail.com"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">jaglazier@gmail.com</a>>;
                <a href="mailto:vp-integration-subgroup@lists.simtk.org"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">vp-integration-subgroup@lists.simtk.org</a>
                <<a
                  href="mailto:vp-integration-subgroup@lists.simtk.org"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">vp-integration-subgroup@lists.simtk.org</a>>;
                Jonathan Karr <<a href="mailto:jonrkarr@gmail.com"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">jonrkarr@gmail.com</a>>;
                John Gennari <<a href="mailto:gennari@uw.edu"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">gennari@uw.edu</a>>;
                Faeder, James R <<a href="mailto:faeder@pitt.edu"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">faeder@pitt.edu</a>>;
                Winston Garira <<a
                  href="mailto:Winston.Garira@univen.ac.za"
                  target="_blank" moz-do-not-send="true"
                  class="moz-txt-link-freetext">Winston.Garira@univen.ac.za</a>><br>
                <b>Subject:</b> Re: [Vp-integration-subgroup]
                [Vp-reproduce-subgroup] Shayn Peirce-Cottler via
                Frontiers: Manuscript</font>
              <div> </div>
            </div>
            <div><font size="2"><span style="font-size:11pt">
                  <div>Dear Jacob,<br>
                    <br>
                    I approve. This version is much better than the
                    earlier one, though it’s a little long. I still
                    prefer the tighter structure of the one that John
                    started.<br>
                    <br>
                    Another example of a model that combines within-host
                    immune dynamics and between-host transmission we’ve
                    just put out (this is together with Ruchira Datta
                    and Veronika Zarnitsyna among others so comes partly
                    out of the MSM innate and adaptive immune response
                    subgroup) is here: <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Farxiv.org%2Fabs%2F2111.02510&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=iRm%2FUvVD%2Fv%2F4ZwpUVFUltZxa6rkbq4uVWOzNdBqdXDk%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Farxiv.org%2Fabs%2F2111.02510&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=iRm%2FUvVD%2Fv%2F4ZwpUVFUltZxa6rkbq4uVWOzNdBqdXDk%3D&amp;reserved=0</a>
                    It gets some interesting results where phenomena
                    that are emergent at the population level arise from
                    simple dynamics at the individual level. Feel free
                    to ignore this though because (a) it’s just a
                    pre-print and (b) this is now fairly late in the
                    game.<br>
                    <br>
                    Could you add a second affiliation for me? School of
                    Informatics, University of Edinburgh<br>
                    <br>
                    Thank you everyone for pulling this together.<br>
                    <br>
                    Cheers,<br>
                    -w<br>
                    <br>
                    <br>
                    > On 6 Nov 2021, at 22:59, Jacob Barhak <<a
                      href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    > <br>
                    > Greetings paper contributors,<br>
                    > <br>
                    > It is time for final approval of our
                    manuscript. Here is the manuscript I ask you to
                    approve towards submission to Frontiers in Systems
                    Biology:<br>
                    > <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit%3Fusp%3Dsharing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=n56Rv%2BYvUgM6I7vvVXKyRUWqf74k6FPR9plverQXDU0%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit%3Fusp%3Dsharing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=n56Rv%2BYvUgM6I7vvVXKyRUWqf74k6FPR9plverQXDU0%3D&amp;reserved=0</a><br>
                    > <br>
                    > I disabled all edits to it at this point so it
                    will not change unless I reopen it.
                    <br>
                    > <br>
                    > This is the list of contributors in no
                    particular order <br>
                    >        • Jonathan Karr, Icahn Institute for
                    Data Science and Genomic Technology and Department
                    of Genetics and Genomic Sciences, Icahn School of
                    Medicine at Mount Sinai, New York, NY, USA<br>
                    >        • Rahuman Sheriff, The European
                    Bioinformatics Institute (EMBL-EBI), London, UK<br>
                    >        • James Osborne, School of Mathematics
                    and Statistics, University of Melbourne, Parkville,
                    Australia<br>
                    >        • Gilberto Gonzalez Parra, Mathematics
                    Department, New Mexico Tech, Socorro, USA<br>
                    >        • Eric Forgoston, Department of Applied
                    Mathematics and Statistics, Montclair State
                    University, Montclair, NJ, USA<br>
                    >        • Ruth Bowness, Department of
                    Mathematical Sciences, University of Bath, Bath, UK<br>
                    >        • Yaling Liu, Department of Mechanical
                    Engineering and Mechanics , Department of
                    Bioengineering, Lehigh University, Bethlehem, PA,
                    USA<br>
                    >        • Robin Thompson, Mathematics Institute
                    & The Zeeman Institute for Systems Biology and
                    Infectious Disease Epidemiology Research, University
                    of Warwick, Coventry , UK<br>
                    >        • Winston Garira - Department Of
                    Mathematics And Applied Mathematics , Modelling
                    Health and Environmental Linkages Research Group.
                    University of Venda, Limpopo, South Africa<br>
                    >        • Jacob Barhak* - Jacob Barhak
                    Analytics, Austin, TX, USA<br>
                    >        • John Rice - Independent Retired
                    Working Group Volunteer, Virginia Beach, VA, USA<br>
                    >        • Marcella Torres*, School of Arts and
                    Sciences, University of Richmond, Richmond, USA<br>
                    >        • Hana M. Dobrovolny , Department of
                    Physics & Astronomy, Texas Christian University,
                    Fort Worth, USA<br>
                    >        • Tingting Tang, Department of
                    Mathematics and Statistics in San Diego State
                    University (SDSU) and SDSU Imperial Valley,
                    Calexico, CA, USA<br>
                    >        • William Waites, Centre for
                    Mathematical Modelling of Infectious Diseases,
                    London School of Hygiene and Tropical Medicine,
                    London, UK<br>
                    >        • James Glazier, Biocomplexity
                    Institute, Indiana University, Bloomington, USA<br>
                    >        • James R. Faeder, Department of
                    Computational and Systems Biology, University of
                    Pittsburgh, Pittsburgh, USA<br>
                    >        • Alexander Kulesza, Novadiscovery SA,
                    Lyon, France<br>
                    > <br>
                    > IF YOU ARE ON THIS LIST - YOU HAVE 3 TASKS DO
                    TO:<br>
                    > <br>
                    > TASK 1: <br>
                    > Please go over the paper and the Journal rules
                    here: <br>
                    > <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fpolicies-and-publication-ethics&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=xDeVGPtW3JEBn%2FKKU5GPMpxsI6vEo7HOuteuRiQHxEw%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fpolicies-and-publication-ethics&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=xDeVGPtW3JEBn%2FKKU5GPMpxsI6vEo7HOuteuRiQHxEw%3D&amp;reserved=0</a>
                    <br>
                    > <br>
                    > Note that the guidelines allow to establish
                    authors levels of contribution according to
                    <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fauthor-guidelines&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=aGORku92DxMHqhJ%2BicF%2BeXULOBQLIjfkFzekQ5XvrU4%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fauthor-guidelines&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=aGORku92DxMHqhJ%2BicF%2BeXULOBQLIjfkFzekQ5XvrU4%3D&amp;reserved=0</a>
                    section 1.9  - however order is not dictated - I
                    suggest to keep this order which is more or less
                    random - I really do not want to discuss order or
                    authors - this is not the purpose of this paper.<br>
                    > Also to simplify the process, I detached the
                    manuscript from the working group - we can add it
                    back according to section 1.10 of the guidelines.
                    For simplicity I suggest we just submit the paper as
                    a group of authors - unless someone volunteers their
                    time to do more paperwork. The working group is
                    mentioned in the paper as well as correspondences.<br>
                    > <br>
                    > TASK 2: <br>
                    > Please check again your name and affiliation is
                    correct. this can be fixed in submission - and
                    apologies in advance for any mistakes. In cases of
                    dual affiliation, I listed only one, so please look
                    at the submission guidelines and give me the correct
                    information according to the guidelines - I will
                    have to enter it manually in the system upon
                    submission. 
                    <br>
                    > <br>
                    > TASK 3: <br>
                    > REPLY TO ALL TO THIS MESSAGE and note one of
                    the following options:<br>
                    >  <br>
                    > 1. APPROVE: this means you agree that the
                    manuscript represents your views correctly  You also
                    approve the corresponding author to act on your
                    behalf for the rest of the publication process -
                    currently I am the corresponding author and will add
                    Marcella if possible yet if anyone else wants to
                    volunteer - please do.<br>
                    > <br>
                    > 2. DISAPPROVE: This means you cannot have your
                    name signed on this manuscript and the group should
                    discuss some matters in further details before
                    submission to properly represent you - this means
                    you are still interested in being an author, yet
                    need your views represented properly - this will
                    delay us all, so if you choose this option, this
                    means you will have to spend time on discussions and
                    explain why you have not acted by now and you are
                    asking to delay now. This option will take a lot of
                    time from you and others, yet you certainly have the
                    right to choose this option. <br>
                    > <br>
                    > 3. ABSTAIN: This means you are ok with removing
                    your name from the author list and allowing the rest
                    of us to submit the manuscript with your
                    contribution without taking responsibility - your
                    name will be added to acknowledgements instead. In
                    legal terms it means you waive copyright on the text
                    you added so we can legally send this text to the
                    Journal despite your name not listed in the author
                    list.
                    <br>
                    > <br>
                    > I also ask John Gennari for the last time to
                    rejoin the group and approve the manuscript as an
                    author sinceI believe he had major contributions -
                    hopefully he will reconsider and accept this
                    responsibility and privilege. Otherwise he makes our
                    lives harder to protect that paper, especially with
                    elements lik SemGen and Annotaions where he is an
                    expert.
                    <br>
                    > <br>
                    > I will need a public response from all of you -
                    if you send me a private email I will forward it to
                    the list to become public record - please avoid
                    doing so since you are making me work twice- so
                    PLEASE PRESS REPLY ALL.<br>
                    > <br>
                    > Hopefully we can get this approval round done
                    quickly and move forward and submit.
                    <br>
                    > <br>
                    >                  Jacob<br>
                    > <br>
                    > <br>
                    > <br>
                    > <br>
                    > On Thu, Nov 4, 2021 at 12:30 AM Jacob Barhak
                    <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    > Thanks James, And Greetings to all
                    contributors, <br>
                    > <br>
                    > James, your suggestions are almost all accepted
                    - yes we needed American English and modelling is
                    not the American form - thanks for noticing. The
                    reference will stay as is or corrected during proofs
                    I see no better way to reference it other than the
                    automatically generated text. <br>
                    > <br>
                    > At this point 3 people went over the manuscript
                    and it seems ready to go.<br>
                    > <br>
                    > However, to avoid any misunderstandings I would
                    like formal public approval from all Authors to make
                    sure we are all on the same page. There were several
                    discussions and different voices and I want to make
                    sure this version is something all authors agree on.
                    Here is the manuscript:<br>
                    > <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit%3Fusp%3Dsharing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=n56Rv%2BYvUgM6I7vvVXKyRUWqf74k6FPR9plverQXDU0%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit%3Fusp%3Dsharing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=n56Rv%2BYvUgM6I7vvVXKyRUWqf74k6FPR9plverQXDU0%3D&amp;reserved=0</a><br>
                    > <br>
                    > If you want to see the comment history, please
                    send me a request so I can add you as an editor.<br>
                    > <br>
                    > Before you rush approving, I would ask you to
                    take a minute and read section 1.3. Authorship and
                    Author Responsibilities in
                    <br>
                    > <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fpolicies-and-publication-ethics&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=xDeVGPtW3JEBn%2FKKU5GPMpxsI6vEo7HOuteuRiQHxEw%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fpolicies-and-publication-ethics&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=xDeVGPtW3JEBn%2FKKU5GPMpxsI6vEo7HOuteuRiQHxEw%3D&amp;reserved=0</a><br>
                    > <br>
                    > If you approve this manuscript, this means you
                    are comfortable with releasing this for publication
                    using the  CC-BY, version 4.0 license with the terms
                    above.
                    <br>
                    > <br>
                    > Please double check your name and affiliation -
                    I will have to copy it - if there is a mistake, let
                    me know.
                    <br>
                    > <br>
                    > If after checking all these you are ok, please:<br>
                    > REPLY TO ALL TO THIS MESSAGE WITH THE TEXT "I
                    APPROVE THE MANUSCRIPT"<br>
                    > <br>
                    > I ask that you do not send any approve message
                    before Saturday - 6 - Nov - I want to give a last
                    chance for edits or discussions before everyone
                    approves. WE had plenty of time, yet I want to make
                    sure there is no late arrival that is very important
                    so I am giving this two more days. <br>
                    > <br>
                    > On Oct 6th I will lock the manuscript and
                    remove all comments and mark them as resolved.
                    <br>
                    > <br>
                    > I hope you all find it in good shape.<br>
                    > <br>
                    >                       Jacob<br>
                    > <br>
                    > <br>
                    > <br>
                    > <br>
                    > On Wed, Nov 3, 2021 at 5:15 AM James Osborne
                    <<a href="mailto:jmosborne@unimelb.edu.au"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jmosborne@unimelb.edu.au</a>>
                    wrote:<br>
                    > Jacob <br>
                    > <br>
                    > I did another readability pass and fixed a few
                    grammatical errors and fixed some British English vs
                    American English inconsistencies (went on the
                    American side). Everything as suggestions so you can
                    leave if you choose.<br>
                    > <br>
                    > For what it's worth thank you for your efforts
                    knocking this into shape.<br>
                    > <br>
                    > James  <br>
                    > <br>
                    > On Wed, Nov 3, 2021 at 4:42 PM Jacob Barhak
                    <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    > Hi James,<br>
                    > <br>
                    > Eric Forgoston was kind enough to gp through
                    the paper and made edits - I resolved most issues
                    and only a few comments are left for experts on
                    annotation and to resolve some differences between
                    John Rice and Alex.
                    <br>
                    > <br>
                    > I ask that we avoid endless edits and start the
                    approval process for submission. We should not drag
                    editing anymore - Eric's last edits were at the
                    level of punctuation and proofs so we should be
                    good. And this is after many edits and checks I made
                    myself and I know Hana and Alex also made edits. <br>
                    > <br>
                    > Unless someone shouts, I will start the
                    approval process tomorrow - so I ask contributors to
                    give the papr a last peek before you are asked to
                    say Yes/NO towards submission with your name on it.
                    <br>
                    > <br>
                    > Hopefully this last warning is sufficient and
                    you will all find the paper in good shape.
                    <br>
                    > <br>
                    >                Jacob<br>
                    > <br>
                    > On Thu, Oct 28, 2021 at 9:26 PM Jacob Barhak
                    <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    > Hi James,<br>
                    > <br>
                    > Apologies - I must have missed your email
                    request. If anyone else wants access and did not get
                    it, please let me know - I will do my best to give
                    you access within a day.
                    <br>
                    > <br>
                    > For those who have access. Please no more
                    additions - from now on just corrections of typos,
                    grammer, and grave errors. Anything else, please
                    leave a comment and we can discuss it.<br>
                    > <br>
                    > I really want the paper out quickly - hopefully
                    we can finish this and submit quickly.<br>
                    > <br>
                    >                Jacob<br>
                    > <br>
                    > On Thu, Oct 28, 2021 at 3:17 PM James A Glazier
                    <<a href="mailto:jaglazier@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jaglazier@gmail.com</a>>
                    wrote:<br>
                    > Dear Jacob:<br>
                    > <br>
                    > I would like to review the document. I had
                    asked for access a few weeks ago. Happy to look in
                    the next few days.<br>
                    > <br>
                    > JAG<br>
                    > <br>
                    > On 10/24/2021 4:40 AM, Jacob Barhak wrote:<br>
                    >> Hi Eric, <br>
                    >> <br>
                    >> You are the last one I remember who wanted
                    to edit. Please check the manuscript<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit%3Fusp%3Dsharing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=n56Rv%2BYvUgM6I7vvVXKyRUWqf74k6FPR9plverQXDU0%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit%3Fusp%3Dsharing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=n56Rv%2BYvUgM6I7vvVXKyRUWqf74k6FPR9plverQXDU0%3D&amp;reserved=0</a><br>
                    >> <br>
                    >> I finished editing the references and am
                    almost ready for transformation to match the
                    guidelines.  I finished addressing the editor
                    requesting for removal of bullet points everywhere
                    but the stochastic section .
                    <br>
                    >> <br>
                    >> I ask that you do not add any more
                    references and focus only on text in the stochastic
                    section. Handling the references took about 4 hours
                    alone and still needs inspection.
                    <br>
                    >> <br>
                    >> However, I will appreciate help with minor
                    proofs - I made significant changes so there is a
                    chance for typos still.  Some of the changes have
                    been made after more than 12 hours of consecutive
                    work. So polish will help - yet no more major
                    changes.
                    <br>
                    >> <br>
                    >> The tasks left to do are:<br>
                    >> - Ask John Gennari to inspect the paper
                    again - it has major contributions from his version
                    and he should join the authors list - I must be ask
                    again
                    <br>
                    >> - Finish the edits to the stochastic
                    section - Eric - you asked for this<br>
                    >> - Finish formatting to fit the Journal
                    guidelines <br>
                    >> - Add a cover letter and split the paper
                    into sections to be uploaded to the journal web site<br>
                    >> - Approve the version with all authors - we
                    must do this again and get full approval - this may
                    take a while<br>
                    >> - Determine who else wants to be listed as
                    corresponding author - currently I marked Marcell
                    and myself, yet others may want to correspond. 
                    <br>
                    >> - Upload the paper to the journal
                    submission system<br>
                    >> <br>
                    >> I hope for no obstacles and full
                    cooperation to make the process smooth.<br>
                    >> <br>
                    >>                      Jacob<br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> On Sat, Oct 23, 2021 at 9:08 PM Jacob
                    Barhak <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    >> So Gilberto,<br>
                    >> <br>
                    >> The last approved version is the only one
                    we can continue from - this is unfortunate that
                    there is a need to back port some modifications -
                    hence the conversation with Eric and Hana - yet to
                    maintain traceability and honor all contributors -
                    this is necessary.<br>
                    >> <br>
                    >> And yes, there will be some differences -
                    it's unavoidable. Yet I pretty much merged the other
                    traceable versions by now. If I missed anything - I
                    apologize - there is a limit to human capabilities.
                    <br>
                    >> <br>
                    >> We discussed this multiple times on this
                    list, if this is a stopper for you, let me know
                    immediately so I will stop work to resolve this
                    issue.<br>
                    >> <br>
                    >> Otherwise, I will continue - I think I
                    resolved most points except from references and
                    removal of bullets - still working on that and I
                    will have to deal with modifying conclusions at the
                    end.
                    <br>
                    >> <br>
                    >> And Gilberto, if you want to contribute
                    time towards changing order of sections and handle
                    references to comply with the target journal
                    guidelines, please go online on the Jitsi
                    channel.and I will show you the extent of work
                    needed. I will be here for at least 3 more hours -
                    until midnight - yet to be efficient, please join on
                    jitsi if you want to talk while I continue
                    modifications.
                    <br>
                    >> <br>
                    >> I hope I can finish most of the work except
                    references perhaps by midnight. <br>
                    >> <br>
                    >>                Jacob<br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> On Sat, Oct 23, 2021 at 8:32 PM Gilberto
                    Gonzalez-Parra <<a
                      href="mailto:gilberto.gonzalezparra@nmt.edu"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">gilberto.gonzalezparra@nmt.edu</a>>
                    wrote:<br>
                    >> Hi Jacob,<br>
                    >> <br>
                    >> I noticed that we are not using the last
                    version that has many modifications. Are you using
                    the previous version that was originally submitted
                    to cureus ? and trying to incorporate the changes of
                    the last version ?<br>
                    >> <br>
                    >> I noticed that the section/challenge
                    Barriers to model implementation and real-world use
                    was removed. I think in one of the emails it says
                    that there is no solution proposed for this. I can
                    write some general ideas for this.
                    <br>
                    >> <br>
                    >> In the current version in the table it
                    appears "<br>
                    >> Model<br>
                    >>  application and implementation barriers<br>
                    >> " just after "<br>
                    >> Missing Annotations in Models"<br>
                    >> <br>
                    >> but later in the document appears just
                    before stochastic modeling. I think we should keep
                    the same order that is in the table. The article<br>
                    >>  would look better organized.<br>
                    >> <br>
                    >> Best,<br>
                    >> <br>
                    >>
***************************************************************************<br>
                    >> Gilberto C. Gonzalez-Parra, Ph.D in Applied
                    Mathematics.<br>
                    >> Faculty of the Mathematics Department<br>
                    >> New Mexico Tech, NM, USA.<br>
                    >>
****************************************************************************<br>
                    >> <br>
                    >> <br>
                    >> On Sat, Oct 23, 2021 at 5:38 PM Jacob
                    Barhak <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    >> Hi Eric, and also greeting for the other
                    paper contributors <br>
                    >> <br>
                    >> Here is a real time update just to give an
                    idea of current editing status.<br>
                    >> <br>
                    >> It took almost 6 hours to get the
                    manuscript to the point that contributions from
                    Sheriff, Alex, John Gennari, and Hana were
                    integrated. I assume Eric will add his edits later -
                    since those are in one section, it should not cause
                    any conflict. However, Eric, please be careful when
                    editing the stochastic section. Pease look at the
                    comments Hana and I exchanged. I am also adding the
                    chat between us so it will be easier on you:<br>
                    >> <br>
                    >> "<br>
                    >> Hi Hana<br>
                    >> Can you see the chat?<br>
                    >> I can. There's just a lot going on around
                    here right now, so I'm not fast with typing<br>
                    >> I put the references in the comments, can
                    you see them?<br>
                    >> Yes I See them - yet you will have to
                    ensure that this is your text - you see, you copied
                    text from a document where we do not have
                    contributor history - this was the main issue - so
                    you will have not to prove this was your text and
                    only your text -  this is the problem I am faced
                    with - I have to establish tracability - in this
                    document I know you added the text - yet I cannot
                    verify that you did not include text from anonymous
                    since I already concluded you added text from Alex -
                    this is how I stumbled on this - I apologize yet I
                    really am serious about tracing back authorship..<br>
                    >> And thanks fro helping<br>
                    >> If you want, you can join jitsi: <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmeet.jit.si%2FCollaborativePaperEditing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=kxHZrZGrcqae4B9YRD1zyUSnZDw3oie7lAmHMAzQb7Q%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmeet.jit.si%2FCollaborativePaperEditing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=kxHZrZGrcqae4B9YRD1zyUSnZDw3oie7lAmHMAzQb7Q%3D&amp;reserved=0</a>  
                    and we can chat using voice<br>
                    >> I just saw your comment - it is public
                    confirmation - this is good enough  thank you
                    <br>
                    >> The first two paragraphs are from the
                    original paper. The third paragraph is from Alex.
                    The last two are mine. It looks like someone (other
                    than me) italicized the in vitro and in vivo and
                    changed the verb on the "Even data that are..." (I
                    had is), but everything else is mine.<br>
                    >> If you can modify things to the original
                    version you added - it will be better - if someone
                    manipulated the text I want to remove it - even if
                    it is small changes
                    <br>
                    >> I know you're trying to get things done
                    today, but I'll be out tonight, so if anything else
                    comes up, I probably won't get to it until the
                    morning.
                    <br>
                    >> Well, "are" is the correct verb there, so
                    that should probably stay. I can remove the
                    italicization.<br>
                    >> Do not worry - I am making good progress
                    and may not need help until I am done - I appreciate
                    the help and the fact you are working on it over the
                    weekend -  I will later also make this chat public
                    for transparency.  I do believe you have contributed
                    a lot to this paper - its not the first time you are
                    going over it - I can only thank you .
                    <br>
                    >> the are was my change today I believe so
                    its not a problem - yet google suggests is instead I
                    guess is and are both acceptable with data ....
                    nevermind that.<br>
                    >> "<br>
                    >> <br>
                    >> I did my best to keep all ideas and other
                    texts intact and there are many comments to mark
                    changes  - the paper became longer, yet not too much
                    and I feel it is still reasonable .<br>
                    >> <br>
                    >> I am now moving to the next part of
                    complying with the requests of the editor:<br>
                    >> 1) Determine authorship<br>
                    >> 2) Converging format to journal guidelines
                    - this also means references<br>
                    >> 3) Detach from group - some elements
                    already marked<br>
                    >> 4) Revise bullet points into paragraphs<br>
                    >> <br>
                    >> I plan to continue editing until midnight
                    CST with a break for dinner - so if anyone has
                    comments - please feel free to join the open channel
                    that shows the editing and influence real-time.<br>
                    >> <br>
                    >> Hopefully you will find the merged version
                    in order. <br>
                    >> <br>
                    >>                Jacob<br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> On Sat, Oct 23, 2021 at 2:50 PM Jacob
                    Barhak <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    >> Hi Eric,<br>
                    >> <br>
                    >> You wanted to edit the stochastic section -
                    you are welcome to do it. Yet I ask no more
                    references or deletions - I am overloaded already.
                    <br>
                    >> <br>
                    >> The version benign edited is:<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=jRu17cEBk1FL0FlwjwNuvx1b5GTWrgBkm0OVXBeVhWE%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=jRu17cEBk1FL0FlwjwNuvx1b5GTWrgBkm0OVXBeVhWE%3D&amp;reserved=0</a><br>
                    >> <br>
                    >> You will need to login so that your edits
                    will be traceable.<br>
                    >> <br>
                    >> You can join me while editing in:<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmeet.jit.si%2FCollaborativePaperEditing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=kxHZrZGrcqae4B9YRD1zyUSnZDw3oie7lAmHMAzQb7Q%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmeet.jit.si%2FCollaborativePaperEditing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727672293%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=kxHZrZGrcqae4B9YRD1zyUSnZDw3oie7lAmHMAzQb7Q%3D&amp;reserved=0</a><br>
                    >> <br>
                    >> I am sharing my screen there while editing.
                    <br>
                    >> <br>
                    >> You might be able to help me with other
                    sections as well.<br>
                    >> <br>
                    >>               Jacob<br>
                    >> <br>
                    >> <br>
                    >> On Sat, Oct 23, 2021 at 2:44 PM Eric
                    Forgoston <<a
                      href="mailto:eric.forgoston@montclair.edu"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">eric.forgoston@montclair.edu</a>>
                    wrote:<br>
                    >> Hi Jacob,<br>
                    >> <br>
                    >> If you give me a link to the paper you are
                    editing and edit access to the paper I can update
                    the stochastic section.<br>
                    >> <br>
                    >> Cheers,<br>
                    >> <br>
                    >> Eric<br>
                    >> ---------------------<br>
                    >> Dr. Eric Forgoston<br>
                    >> Professor of Applied Mathematics<br>
                    >> Chair, Department of Applied Mathematics
                    and Statistics<br>
                    >> Montclair State University<br>
                    >> Montclair, NJ  07043 USA<br>
                    >> +1 973 655-7242 <br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Feric-forgoston.github.io%2F&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=KiG9WrIyZdyq8WdZIIzMD2GV86jcFjgPzhkKxwChSRM%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Feric-forgoston.github.io%2F&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=KiG9WrIyZdyq8WdZIIzMD2GV86jcFjgPzhkKxwChSRM%3D&amp;reserved=0</a><br>
                    >> <br>
                    >> <br>
                    >> On Sat, Oct 23, 2021 at 1:39 PM Jacob
                    Barhak <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    >> Greetings Paper Contributors,<br>
                    >> <br>
                    >> The paper editing process started and you
                    can follow it live on:<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmeet.jit.si%2FCollaborativePaperEditing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=KHnJGERu2bWXaAIOyq8eOupzextaxY7R2rnFh6L9C4Y%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmeet.jit.si%2FCollaborativePaperEditing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=KHnJGERu2bWXaAIOyq8eOupzextaxY7R2rnFh6L9C4Y%3D&amp;reserved=0</a><br>
                    >> <br>
                    >> I will keep the channel open as long as I
                    am editing so that the process will be as
                    transparent as possible.
                    <br>
                    >> <br>
                    >> The first step would be to reconcile the
                    differences between those 4 versions traceable back
                    to authors:<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=I6DsF2ivsYWpSZQgJitLeCia%2FSUA8CI%2BqBzIM9FWv0s%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1IMEgmdNkx-EsnOjGuegpenSIMmKIkK00Lc8Gred3QxM%2Fedit&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=I6DsF2ivsYWpSZQgJitLeCia%2FSUA8CI%2BqBzIM9FWv0s%3D&amp;reserved=0</a> 
                    - the submitted version<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1VvyP3YZQdQYjj8DFKOpQ4pn_0pdDGgiT%2Fedit&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=KaQhYbqzSI41r7YtAEa5DXbGFKDMCzt0q9zanMv7vpk%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1VvyP3YZQdQYjj8DFKOpQ4pn_0pdDGgiT%2Fedit&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=KaQhYbqzSI41r7YtAEa5DXbGFKDMCzt0q9zanMv7vpk%3D&amp;reserved=0</a> 
                    - first committed version<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1Ag4ipuybjtthxgV0YjXqYP7AwwNSYcWh%2Fedit&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=ZfpwZxECQgRrBzqp5y3Xbl%2FdkFjPdnASuULrlKag36c%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1Ag4ipuybjtthxgV0YjXqYP7AwwNSYcWh%2Fedit&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=ZfpwZxECQgRrBzqp5y3Xbl%2FdkFjPdnASuULrlKag36c%3D&amp;reserved=0</a> 
                    - first committed version<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdrive.google.com%2Ffile%2Fd%2F1U_lTHrV6STXWNT3GiCepvsLk1WdYgzN5%2Fview&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=7pp2qxmQKnhvW%2Fplmg9Qv6l%2FfO6nz42Z7GF2ehRu%2Fa8%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdrive.google.com%2Ffile%2Fd%2F1U_lTHrV6STXWNT3GiCepvsLk1WdYgzN5%2Fview&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=7pp2qxmQKnhvW%2Fplmg9Qv6l%2FfO6nz42Z7GF2ehRu%2Fa8%3D&amp;reserved=0</a>
                    - its the first document posted<br>
                    >> <br>
                    >> After this step is done I will move towards
                    adhering to those instructions:<br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fauthor-guidelines&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=qkqzufzA1m6zgRR9gppIq4%2B2LYYByiBhRQAamQntqTM%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fauthor-guidelines&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=qkqzufzA1m6zgRR9gppIq4%2B2LYYByiBhRQAamQntqTM%3D&amp;reserved=0</a><br>
                    >> <br>
                    >> I estimate I will be working till late
                    today with very few breaks and hopefully make
                    sufficient progress.<br>
                    >> <br>
                    >> Feel free to visit and perhaps even help.
                    If you do, please raise your voice so I can hear you
                    - I am sharing my screen and not seeing the video
                    when I edit - so you will have to let me know you
                    are in the room.
                    <br>
                    >> <br>
                    >> Hopefully some of you will visit.<br>
                    >> <br>
                    >>               Jacob<br>
                    >> <br>
                    >> On Fri, Oct 22, 2021 at 2:52 PM Jacob
                    Barhak <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    >> Thanks Sheriff,  <br>
                    >> <br>
                    >> With your green light I can start editing<br>
                    >> <br>
                    >> Eric,  the base of John's version will be
                    merged to the best of my ability, yet unfortunately,
                    it has omissions and later version based on it are
                    not traceable back to contributors,  so I can only
                    use some of  the base.
                    <br>
                    >> <br>
                    >> If you want to repeat edits so those will
                    be traceable it is possible. Yet we cannot copy
                    verbatim without going to details.
                    <br>
                    >> <br>
                    >> To make things easier,  I will open a
                    channel over the weekend during edits where anyone
                    can join and communicate while watching the edits
                    live. 
                    <br>
                    >> <br>
                    >> Hopefully it will make things smoother. <br>
                    >> <br>
                    >>             Jacob<br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> <br>
                    >> On Fri, Oct 22, 2021, 13:40 Eric Forgoston
                    <<a href="mailto:eric.forgoston@montclair.edu"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">eric.forgoston@montclair.edu</a>>
                    wrote:<br>
                    >> Dear Jacob and all,<br>
                    >> <br>
                    >> I suggest, as others have done, to use the
                    John G. version as structurally it has already
                    cleaned up most of the issues raised by the Editor,
                    and also has many revised and improved sections. In
                    particular, the stochastic section that I worked on
                    with others is far superior to the one in the paper
                    submitted to Frontiers.<br>
                    >> <br>
                    >> Best wishes,<br>
                    >> <br>
                    >> Eric<br>
                    >> ---------------------<br>
                    >> Dr. Eric Forgoston<br>
                    >> Professor of Applied Mathematics<br>
                    >> Chair, Department of Applied Mathematics
                    and Statistics<br>
                    >> Montclair State University<br>
                    >> Montclair, NJ  07043 USA<br>
                    >> +1 973 655-7242 <br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Feric-forgoston.github.io%2F&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=KiG9WrIyZdyq8WdZIIzMD2GV86jcFjgPzhkKxwChSRM%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Feric-forgoston.github.io%2F&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=KiG9WrIyZdyq8WdZIIzMD2GV86jcFjgPzhkKxwChSRM%3D&amp;reserved=0</a><br>
                    >> <br>
                    >> <br>
                    >> On Fri, Oct 22, 2021 at 12:57 PM Rahuman
                    Sheriff <<a href="mailto:sheriff@ebi.ac.uk"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">sheriff@ebi.ac.uk</a>>
                    wrote:<br>
                    >> Congratulations Marcella,<br>
                    >> <br>
                    >> Hi Jacob and all,<br>
                    >> <br>
                    >> As Tomas mentioned, John G’s version is bit
                    more organised.  <br>
                    >> Although it would be nice to take that one
                    forward, I also fine with you recovering your
                    version incorporating requested changes including
                    mine.
                    <br>
                    >> I would prefer this manuscript progresses
                    ahead, instead of another long discussion. 
                    <br>
                    >> Green signal from my side.<br>
                    >> Best regards<br>
                    >> Sheriff<br>
                    >> <br>
                    >> <br>
                    >>> On 22 Oct 2021, at 01:49, Jacob Barhak
                    <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    >>> <br>
                    >>> Congratulations Marcella, <br>
                    >>> <br>
                    >>> Indeed you bring good news. <br>
                    >>> <br>
                    >>> You should not worry about the
                    manuscript.  You have done plenty and we can handle
                    if from now on,  you can focus on your family.
                    <br>
                    >>> <br>
                    >>>          Jacob<br>
                    >>> <br>
                    >>> On Thu, Oct 21, 2021, 10:33 Torres,
                    Marcella <<a href="mailto:mtorres@richmond.edu"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">mtorres@richmond.edu</a>>
                    wrote:<br>
                    >>> This streamlined approach sounds good
                    to me; thanks Jacob for offering to coordinate
                    edits. I think the one month deadline is a good
                    maximum, since Frontiers favors quick turnaround.<br>
                    >>> <br>
                    >>> I don't insist on participating in the
                    revisions, but I am available to help with cleaning
                    up grammar, typos, and so on - I noticed quite a few
                    minor issues when reviewing the document for
                    submission. However, my son was born a few days ago
                    and I have limited time. <br>
                    >>> <br>
                    >>> Marcella<br>
                    >>> From: Jacob Barhak <<a
                      href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>><br>
                    >>> Sent: Wednesday, October 20, 2021
                    11:53:58 PM<br>
                    >>> To: Alexander Kulesza <<a
                      href="mailto:alexander.kulesza@novadiscovery.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">alexander.kulesza@novadiscovery.com</a>><br>
                    >>> Cc: Hana <<a
                      href="mailto:h.dobrovolny@tcu.edu" target="_blank"
                      moz-do-not-send="true"
                      class="moz-txt-link-freetext">h.dobrovolny@tcu.edu</a>>;
                    James Osborne <<a
                      href="mailto:jmosborne@unimelb.edu.au"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jmosborne@unimelb.edu.au</a>>;
                    John Rice <<a href="mailto:john.rice@noboxes.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">john.rice@noboxes.org</a>>;
                    Torres, Marcella <<a
                      href="mailto:mtorres@richmond.edu" target="_blank"
                      moz-do-not-send="true"
                      class="moz-txt-link-freetext">mtorres@richmond.edu</a>>;
                    <a
                      href="mailto:vp-reproduce-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">vp-reproduce-subgroup@lists.simtk.org</a>
                    <<a
                      href="mailto:vp-reproduce-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">vp-reproduce-subgroup@lists.simtk.org</a>>;
                    <a
                      href="mailto:vp-integration-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">vp-integration-subgroup@lists.simtk.org</a>
                    <<a
                      href="mailto:vp-integration-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">vp-integration-subgroup@lists.simtk.org</a>>;
                    Jonathan Karr <<a
                      href="mailto:jonrkarr@gmail.com" target="_blank"
                      moz-do-not-send="true"
                      class="moz-txt-link-freetext">jonrkarr@gmail.com</a>>;
                    John Gennari <<a href="mailto:gennari@uw.edu"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">gennari@uw.edu</a>>;
                    Winston Garira <<a
                      href="mailto:Winston.Garira@univen.ac.za"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">Winston.Garira@univen.ac.za</a>><br>
                    >>> Subject: Re: [Vp-integration-subgroup]
                    Fwd: Shayn Peirce-Cottler via Frontiers: Manuscript<br>
                    >>>  <br>
                    >>> External Email: Use caution in opening
                    links, attachments, and buying gift cards.<br>
                    >>> <br>
                    >>> Thanks Alex, Thanks John,<br>
                    >>> <br>
                    >>> Your contribution is appreciated and
                    since John cleared us to move forward it simplifies
                    things. I hope he will change his mind about
                    authorship since he contributed a lot, yet I will
                    respect his wishes - perhaps after seeing the final
                    version he will change his mind. <br>
                    >>> <br>
                    >>> If Sheriff gives me a green light I can
                    incorporate his modifications as well. I do ask that
                    if any of the listed authors has any serious
                    concerns and plans to not approve a modified version
                    that addresses the editors requests alone alongside
                    those I mentioned above, to step up before the work
                    is done so we can resolve things before energy is
                    spent.
                    <br>
                    >>> <br>
                    >>> If there will be no blocks I plan to
                    start work over the weekend if I see no objections
                    by then.<br>
                    >>> <br>
                    >>> I appreciate the offer to help with
                    bibliography, from experience I know it is perhaps
                    the most time consuming. However, since we have many
                    links and specialized publications in our list - I
                    am not sure if any tool can make it easier - the
                    last time I had to do a lot of manual work to fit a
                    specific format and find all missing links and also
                    fix some errors - no tool would have helped me then.
                    This time I think it will be a bit easier. Yet I ask
                    for no more references to be added - I also want to
                    add more references, yet I am stopping myself. We
                    can always expand the work in another future version
                    if we have new findings.
                    <br>
                    >>> <br>
                    >>> Again note that I will only try to
                    address the requests of the editor at this point
                    without trying to perfect anything beyond what I
                    wrote above and I want to keep things as traceable
                    as possible. Once I am done,we will see if we can
                    approve this manuscript for publication.<br>
                    >>> <br>
                    >>> Unless any blockers appear, if anyone
                    wants to actively participate in the editing over
                    the weekend, please let me know so we can
                    communicate better.<br>
                    >>> <br>
                    >>>             Jacob<br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> On Tue, Oct 19, 2021 at 2:02 AM
                    Alexander Kulesza <<a
                      href="mailto:alexander.kulesza@novadiscovery.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">alexander.kulesza@novadiscovery.com</a>>
                    wrote:<br>
                    >>> Dear Jacob,<br>
                    >>> thanks for forwarding and you
                    suggestions, which seems more than reasonable. <br>
                    >>> <br>
                    >>> My contributions from May 19th, May31st
                    and June 2nd are in <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1VvyP3YZQdQYjj8DFKOpQ4pn_0pdDGgiT%2Fedit%3Fusp%3Dsharing%26ouid%3D113860487708206439519%26rtpof%3Dtrue%26sd%3Dtrue&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=5DkphKFgmXWvV4azKVy0EyqJwh3cnPbocnBSE%2BL8CZQ%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1VvyP3YZQdQYjj8DFKOpQ4pn_0pdDGgiT%2Fedit%3Fusp%3Dsharing%26ouid%3D113860487708206439519%26rtpof%3Dtrue%26sd%3Dtrue&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=5DkphKFgmXWvV4azKVy0EyqJwh3cnPbocnBSE%2BL8CZQ%3D&amp;reserved=0</a>
                    <br>
                    >>> <br>
                    >>> The other document <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1esZvWWVBvpwvuFUi3C3161lthZkEBFyMRrwwozitBi4%2Fedit%3Fusp%3Dsharing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=i69lTB9BmMlCGAivRn4Z5ZXIayBAK9UYcKmumIsr6TY%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fdocument%2Fd%2F1esZvWWVBvpwvuFUi3C3161lthZkEBFyMRrwwozitBi4%2Fedit%3Fusp%3Dsharing&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=i69lTB9BmMlCGAivRn4Z5ZXIayBAK9UYcKmumIsr6TY%3D&amp;reserved=0</a>
                    I created initially to suggest my edits without
                    editing the core version can be disregarded as I
                    have tranferred all of them into the main document,
                    cited above.
                    <br>
                    >>> <br>
                    >>> If we were on Latex, I could offer to
                    create the bibliography but unfortunately we lack a
                    bibliography manager integrated in Word/GDoc. If we
                    were to work with Mendeley and someone could create
                    a group for this paper that has a shared library I
                    could offer to transfer citations from the paper
                    into that database too. <br>
                    >>> <br>
                    >>> Please let me know.<br>
                    >>> A<br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> On Tue, 19 Oct 2021 at 05:51, Jacob
                    Barhak <<a href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>>
                    wrote:<br>
                    >>> Greetings white paper contributors,<br>
                    >>> <br>
                    >>> Below is the response from the editor
                    to my request and my thank you.<br>
                    >>> <br>
                    >>> The editor grants us the extension by
                    rejecting the paper and allowing time to come up
                    with a better version. There is no time limit now,
                    yet I want to get her a revised version within a
                    month.
                    <br>
                    >>> <br>
                    >>> The requests are simple and easy to
                    satisfy - and I know there are many of you who want
                    more revisions, yet I suggest we reduce them to only
                    what is manageable and necessary. Otherwise we will
                    never get this paper published despite its
                    importance.
                    <br>
                    >>> <br>
                    >>> The most time consuming effort would be
                    adhering to the journal format as defined here:<br>
                    >>> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fauthor-guidelines&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=qkqzufzA1m6zgRR9gppIq4%2B2LYYByiBhRQAamQntqTM%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fabout%2Fauthor-guidelines&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=qkqzufzA1m6zgRR9gppIq4%2B2LYYByiBhRQAamQntqTM%3D&amp;reserved=0</a><br>
                    >>> <br>
                    >>> I think the most time consuming task
                    would be dealing with the references - otherwise the
                    format guidelines seem reasonable.<br>
                    >>> <br>
                    >>> We can also add some revisions we
                    started working on. However, I will personally
                    insist on :<br>
                    >>> 1. traceability - currently there is no
                    traceability in the revised version in the summer<br>
                    >>> 2. non deletion - do not delete any
                    content unless you wrote it originally or unless you
                    announced it beforehand to the group and got no
                    objections within a few days
                    <br>
                    >>> 3. Avoid Adding more material that is
                    not in the existing versions we had - especially
                    references - we don't have time for that and that is
                    not what the editor asked us anyway.
                    <br>
                    >>> <br>
                    >>> I will also ask for fast responses from
                    all contributors. <br>
                    >>> <br>
                    >>> To be practical, I marked the submitted
                    version and opened the document to those who
                    requested editing rights in the past.  If you want
                    editing rights, let me know - however, the edits
                    should be minimal and focus on areas you edited in
                    the past and be aware that if your edits will not
                    get approved by everyone, we will revert to the old
                    version we all accepted. The submitted version was
                    marked so we can always get back to it.
                    <br>
                    >>> <br>
                    >>> If you want editing rights, let me know
                    and I will respond within a day - I cannot promise
                    to be fatter than that these days.
                    <br>
                    >>> <br>
                    >>> Alex, John, Sheriff, you had other
                    versions you created, I want to merge some of your
                    changes to the manuscript in this version - here are
                    my suggestions:<br>
                    >>> <br>
                    >>> - Sheriff, I will soften the language
                    as you requested - this was your main request in the
                    past, yet I will go over your list of changes and
                    see what I else can be done without reinventing the
                    paper<br>
                    >>> - John - I will 1) merge the
                    credibility sections , 2) delete the history related
                    to the working group since it matches with what was
                    requested, and 3) move the model validation barrier
                    section away from the table since we did not suggest
                    a solution there.  Hopefully this will make the
                    paper more appealing to you and you will be willing
                    to add your name to the list 
                    <br>
                    >>> - Alex, your changes were made on May
                    16, 2021 and shared in a way I can see the
                    differences and trace them back to you - I will try
                    to add your references and see if I can incorporate
                    your text changes as much as I can.
                    <br>
                    >>> <br>
                    >>> If the 3 of you are ok with me
                    migrating your changes, I can start the work to save
                    time. Yet I want your ok first.
                    <br>
                    >>> <br>
                    >>> I know Eric and Hana were working on
                    some sections and feel strongly about those -
                    specifically the stochastic modeling part - I am
                    open to your changes, please suggest what you feel
                    strongly about..<br>
                    >>> <br>
                    >>> I recall Johnathan Karr wanted to make
                    some changes, please let me know if there is
                    anything you feel strongly about - he had a lot of
                    text in the paper ..<br>
                    >>> <br>
                    >>> If I forgot anyone who had major
                    requests, please remind me. .<br>
                    >>> <br>
                    >>> I am trying to avoid a never ending
                    revisioning cycle. So I am asking you to trust me
                    and centralize the work in hope I get a better
                    version by the end of the week..<br>
                    >>> <br>
                    >>> Hopefully most of you will be ok with
                    that.<br>
                    >>> <br>
                    >>>                Jacob<br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> ---------- Forwarded message ---------<br>
                    >>> From: Jacob Barhak <<a
                      href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>><br>
                    >>> Date: Mon, Oct 18, 2021 at 9:34 PM<br>
                    >>> Subject: Re: Shayn Peirce-Cottler via
                    Frontiers: Manuscript<br>
                    >>> To: Peirce-Cottler, Shayn (smp6p) <<a
                      href="mailto:smp6p@virginia.edu" target="_blank"
                      moz-do-not-send="true"
                      class="moz-txt-link-freetext">smp6p@virginia.edu</a>><br>
                    >>> Cc: Shayn Peirce-Cottler (Via
                    FrontiersIn) <<a href="mailto:shayn@virginia.edu"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">shayn@virginia.edu</a>>,<a
href="mailto:systemsbiology.editorial.office@frontiersin.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">systemsbiology.editorial.office@frontiersin.org</a>
                    <<a
                      href="mailto:systemsbiology.editorial.office@frontiersin.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">systemsbiology.editorial.office@frontiersin.org</a>>,
                    Vodovotz, Yoram <<a
                      href="mailto:vodovotzy@upmc.edu" target="_blank"
                      moz-do-not-send="true"
                      class="moz-txt-link-freetext">vodovotzy@upmc.edu</a>><br>
                    >>> <br>
                    >>> <br>
                    >>> Thanks Shayn,<br>
                    >>> <br>
                    >>> You will get a revised manuscript
                    targeted at your journal and get back to you with a
                    more polished version and satisfies your requests.
                    <br>
                    >>> <br>
                    >>> It will also allow us to incorporate
                    newer versions of the text that answer some of your
                    requests. We really wish to publish it fast, yet we
                    need more time for the approval process. So your
                    solution seems correct - I hope you hear back from
                    us within a month or so.<br>
                    >>> <br>
                    >>> Many thanks for the rapid responses.<br>
                    >>> <br>
                    >>>                  Jacob<br>
                    >>> <br>
                    >>> <br>
                    >>> --<br>
                    >>> Jacob Barhak Ph.D. <br>
                    >>> Sole Proprietor, Software Developer,
                    and Computational Disease Modeler<br>
                    >>> <br>
                    >>> Jacob Barhak Analytics<br>
                    >>> 701 Brazos St<br>
                    >>> Suite 548<br>
                    >>> Austin TX, 78701<br>
                    >>> <br>
                    >>> Email: <a
                      href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a><br>
                    >>> <br>
                    >>> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fsites.google.com%2Fview%2Fjacob-barhak%2Fhome&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=gOmUYx5pQzFybacMWUfy9v7oUfcEPnCBBOzOQdICYoU%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fsites.google.com%2Fview%2Fjacob-barhak%2Fhome&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727682287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=gOmUYx5pQzFybacMWUfy9v7oUfcEPnCBBOzOQdICYoU%3D&amp;reserved=0</a><br>
                    >>> <br>
                    >>> <br>
                    >>> <br>
                    >>> On Mon, Oct 18, 2021 at 7:43 PM
                    Peirce-Cottler, Shayn (smp6p) <<a
                      href="mailto:smp6p@virginia.edu" target="_blank"
                      moz-do-not-send="true"
                      class="moz-txt-link-freetext">smp6p@virginia.edu</a>>
                    wrote:<br>
                    >>> Hi Jacob, <br>
                    >>> <br>
                    >>>  <br>
                    >>> Thank you for your detailed reply. I
                    agree that the issues can be addressed as you have
                    described below, and that you may need more time to
                    do so. Hence, I am going to officially reject this
                    first submission to remove any imposed deadlines,
                    and I certainly encourage you to make the updates
                    listed below, and submit a new manuscript at your
                    earliest convenience. 
                    <br>
                    >>> <br>
                    >>>  <br>
                    >>> Please let me know if you have any
                    questions, and thanks again for considering this
                    journal! I think the topic fits very nicely with the
                    scope of the journal, and it is certainly an
                    important topic to our multi-scale modeling
                    community!<br>
                    >>> <br>
                    >>>  <br>
                    >>> -Shayn<br>
                    >>> <br>
                    >>>  <br>
                    >>>  <br>
                    >>> Shayn Peirce-Cottler, Ph.D.<br>
                    >>> <br>
                    >>> Professor of Biomedical Engineering<br>
                    >>> <br>
                    >>> Harrison Distinguished Teaching
                    Professor<br>
                    >>> <br>
                    >>> BME Graduate Program Director<br>
                    >>> <br>
                    >>> University of Virginia<br>
                    >>> <br>
                    >>> Charlottesville, VA<br>
                    >>> <br>
                    >>>  <br>
                    >>> From: Jacob Barhak <<a
                      href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a>><br>
                    >>> Date: Monday, October 18, 2021 at 1:57
                    AM<br>
                    >>> To: Peirce-Cottler Shayn <<a
                      href="mailto:shayn@virginia.edu" target="_blank"
                      moz-do-not-send="true"
                      class="moz-txt-link-freetext">shayn@virginia.edu</a>><br>
                    >>> Cc: "<a
                      href="mailto:systemsbiology.editorial.office@frontiersin.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">systemsbiology.editorial.office@frontiersin.org</a>"
                    <<a
                      href="mailto:systemsbiology.editorial.office@frontiersin.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">systemsbiology.editorial.office@frontiersin.org</a>>,
                    "Vodovotz, Yoram" <<a
                      href="mailto:vodovotzy@upmc.edu" target="_blank"
                      moz-do-not-send="true"
                      class="moz-txt-link-freetext">vodovotzy@upmc.edu</a>><br>
                    >>> Subject: Re: Shayn Peirce-Cottler via
                    Frontiers: Manuscript<br>
                    >>> <br>
                    >>>  <br>
                    >>> Hi Shayn,<br>
                    >>> <br>
                    >>>  <br>
                    >>> Thanks for returning the response
                    quickly. To you comments. <br>
                    >>> <br>
                    >>>  <br>
                    >>> 1. This is the list of authors that
                    agreed to submit this manuscript for review - I
                    collected their approvals for this version
                    personally.
                    <br>
                    >>> <br>
                    >>>  <br>
                    >>>      • Jonathan Karr, Icahn Institute
                    for Data Science and Genomic Technology and
                    Department of Genetics and Genomic Sciences, Icahn
                    School of Medicine at Mount Sinai USA<br>
                    >>>      • Rahuman Sheriff, The European
                    Bioinformatics Institute (EMBL-EBI), UK<br>
                    >>>      • James Osborne, School of
                    Mathematics and Statistics, University of Melbourne,
                    Australia<br>
                    >>>      • Gilberto Gonzalez Parra,
                    Mathematics Department, New Mexico Tech, USA<br>
                    >>>      • Eric Forgoston, Department of
                    Applied Mathematics and Statistics, Montclair State
                    University, USA<br>
                    >>>      • Ruth Bowness, Department of
                    Mathematical Sciences, University of Bath, UK<br>
                    >>>      • Yaling Liu, Department of
                    Mechanical Engineering and Mechanics , Department of
                    Bioengineering, Lehigh University, USA<br>
                    >>>      • Robin Thompson, Mathematics
                    Institute & The Zeeman Institute for Systems
                    Biology and Infectious Disease Epidemiology
                    Research, University of Warwick, UK<br>
                    >>>      • Winston Garira - Department Of
                    Mathematics And Applied Mathematics , Modelling
                    Health and Environmental Linkages Research Group.
                    University of Venda, South Africa<br>
                    >>>      • Jacob Barhak - Barhak, Jacob,
                    USA<br>
                    >>>      • John Rice - Independent Retired
                    Working Group Volunteer, USA<br>
                    >>>      • Marcella Torres, School of Arts
                    and Sciences, University of Richmond, USA<br>
                    >>>      • Hana M. Dobrovolny , Department
                    of Physics & Astronomy, Texas Christian
                    University, Fort Worth, USA<br>
                    >>>      • Tingting Tang, Department of
                    Mathematics and Statistics in San Diego State
                    University (SDSU) and SDSU Imperial Valley, USA<br>
                    >>>      • William Waites, Centre for
                    Mathematical Modelling of Infectious Diseases,
                    London School of Hygiene and Tropical Medicine, UK<br>
                    >>>      • James Glazier, Biocomplexity
                    Institute, Indiana University, Bloomington, USA<br>
                    >>>      • James R. Faeder, Department of
                    Computational and Systems Biology, University of
                    Pittsburgh, Pittsburgh, USA<br>
                    >>>  <br>
                    >>> If there is a mismatch of authors in
                    the submission, it can be easily corrected - we kept
                    the paper traceable when we constructed it so we can
                    point to exact texts contributed by each contributor
                    through their google account and versions kept in
                    google docs with few exceptions where I personally
                    added text their wrote and have email conversations
                    supporting that .  I personally collected all those
                    contributions in google docs when I assembled the
                    version you see and made sure it is agreed upon by
                    the contributors. It is important to note that There
                    was one contributor that asked for more revisions
                    and did not approve this manuscript, yet allowed
                    submitting the text without association to it to
                    avoid delays. The entire conversation was documented
                    publicly in our mailing list and we got consent from
                    this contributor to continue and use the text - You
                    can find the conversation  here:
                    <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fpipermail%2Fvp-reproduce-subgroup%2F2021-March%2F000019.html&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=ia5ARWxyBl%2BY%2B11jfwExOLPPxpbhGaqtktpYk1Cyp3c%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fpipermail%2Fvp-reproduce-subgroup%2F2021-March%2F000019.html&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=ia5ARWxyBl%2BY%2B11jfwExOLPPxpbhGaqtktpYk1Cyp3c%3D&amp;reserved=0</a> 
                    -  so there are no copyright issues and the name of
                    the author is not included in the list above at
                    their request. Those included in the list have
                    contributed and approved. If needed, we will correct
                    the list in the journal to match this list. Please
                    note that we kept the entire process as transparent
                    as possible so there will be no issues. If there are
                    any concerns of authorship, I will be happy to dig
                    into the history and pull out details.
                    <br>
                    >>> <br>
                    >>>  <br>
                    >>>  <br>
                    >>> 2. The reason the manuscript was
                    submitted in this form is to get confirmation on
                    initial fit and to get some initial feedback. We
                    were interested in fast review to get the
                    information quickly out - Also note that we did not
                    intend this to be a final version - we already have
                    some modifications in the work that we would like to
                    introduce where more people contributed , yet we
                    have not reached agreement on those so we cannot
                    formally publish them - however, we did reach
                    agreement on submitting this version for review so
                    the editor can focus us on what is important to
                    change to get published with a 3rd Party - enough of
                    us agreed in a vote that your Journal seems is a
                    suitable 3rd party and hence the submission. We will
                    be happy to spend the time to convert the manuscript
                    to the desired format if you find the content
                    suitable for the journal. So far your requests are
                    reasonable and I will convey them to the group
                    through our mailing list.
                    <br>
                    >>> <br>
                    >>>  <br>
                    >>> 3. Please note that after the list of
                    authors there is a disclaimer : "The opinion of the
                    contributors do not reflect the opinions of the
                    entire working group". Initially this paper started
                    as an activity requested by the working group leads.
                    However, by no means it represents all opinions. The
                    introduction in this version of the paper captures
                    some of this history of how the manuscript was
                    created and modified. However, we have other
                    versions of the manuscript in work where this
                    history is deleted - If you prefer, we can easily
                    create a version that detaches from the working
                    group to eliminate all concerns - this is a
                    relatively easy fix. However, whatever fix we do, we
                    will have to approve with all contributors.
                    <br>
                    >>> <br>
                    >>>  <br>
                    >>> 4  The revisions can be done in
                    reasonable time. However, the process of collecting
                    approval for all contributors to legally approve the
                    revised manuscript will take more than 14 days. All
                    contributors must approve a manuscript for
                    publication. With this number of authors we will
                    probably not make it in the time you mentioned -
                    only the approval process for collecting all
                    approvals took alone about 3 weeks to approve this
                    version you see.  Hopefully you will understand this
                    and extend this time period beyond 14 days. <br>
                    >>> <br>
                    >>>  <br>
                    >>> In summary: <br>
                    >>> <br>
                    >>> Making the fixes you asked for towards
                    publication is easy - yet getting the approval from
                    so many people may take us more time than what you
                    provide. If it is possible to get an extension, it
                    will be appreciated.
                    <br>
                    >>> <br>
                    >>>  <br>
                    >>> I will add this conversation to our
                    mailing list so we can start the process of revising
                    the manuscript.  However, if after this email you
                    have more issues with this paper, Please advise on
                    the best course of action you see fit so we can
                    adjust accordingly.
                    <br>
                    >>> <br>
                    >>>  <br>
                    >>> Hopefully we can address your concerns
                    in time to publish the manuscript in a timely
                    manner.
                    <br>
                    >>> <br>
                    >>>  <br>
                    >>>                  Jacob<br>
                    >>> <br>
                    >>>  <br>
                    >>> --<br>
                    >>> Jacob Barhak Ph.D. <br>
                    >>> Sole Proprietor, Software Developer,
                    and Computational Disease Modeler<br>
                    >>> <br>
                    >>> Jacob Barhak Analytics<br>
                    >>> 701 Brazos St<br>
                    >>> Suite 548<br>
                    >>> Austin TX, 78701<br>
                    >>> <br>
                    >>> Email: <a
                      href="mailto:jacob.barhak@gmail.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">jacob.barhak@gmail.com</a><br>
                    >>> <br>
                    >>> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fsites.google.com%2Fview%2Fjacob-barhak%2Fhome&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=Ce1AaYV56fay8a5ng%2FtH8OhrVLjo9344eynKrsKrx5I%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fsites.google.com%2Fview%2Fjacob-barhak%2Fhome&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=Ce1AaYV56fay8a5ng%2FtH8OhrVLjo9344eynKrsKrx5I%3D&amp;reserved=0</a><br>
                    >>> <br>
                    >>>  <br>
                    >>>  <br>
                    >>> On Sun, Oct 17, 2021 at 9:56 AM Shayn
                    Peirce-Cottler (Via FrontiersIn) <<a
                      href="mailto:noreply@frontiersin.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">noreply@frontiersin.org</a>>
                    wrote:<br>
                    >>> <br>
                    >>> Dear Jacob, <br>
                    >>> <br>
                    >>> Thank you for your manuscript
                    submission. I cannot send it out for review in its
                    current form because I have a few concerns, but if
                    you can address the following issues, I will
                    certainly reconsider a revised manuscript if the
                    following are adequately addressed:<br>
                    >>> <br>
                    >>> 1. The author list that is on the first
                    page differs from the author list that was provided
                    at the time of submission.
                    <br>
                    >>> <br>
                    >>> 2. The manuscript needs to be submitted
                    using the official Frontiers template.<br>
                    >>> <br>
                    >>> 3. The manuscript states that it
                    represents the views of a number of special interest
                    and working groups, and the authors should provide
                    assurances that they have the authority and approval
                    to speak on behalf of the working groups that are
                    listed.<br>
                    >>> <br>
                    >>> 4. There are places throughout the
                    manuscript, and most frequently in the second half,
                    where information is provided as bulleted talking
                    points without context. Those sections should be
                    revised into paragraphs of text or summarized in a
                    table (or figure).<br>
                    >>> <br>
                    >>> If you wish to submit a revised
                    manuscript, the journal provides a 14-day time
                    window for you to do so. Please let me know if you
                    have any questions.
                    <br>
                    >>> <br>
                    >>> Thank you,<br>
                    >>> Shayn<br>
                    >>> <br>
                    >>> <br>
                    >>> ---------------------------------<br>
                    >>> <br>
                    >>> Manuscript title: Model Integration in
                    Computational Biology: The Role of Reproducibility,
                    Credibility and Utility<br>
                    >>> Manuscript ID: 793932<br>
                    >>> Authors: Marcella Torres, Jacob Barhak,
                    Ruth Bowness, Hana Maria Dobrovolny, James Faeder,
                    Eric Forgoston, Winston Garira, Yaling Liu, James
                    Osborne, Gilberto Gonzalez Parra, John Rice, Rahuman
                    Sheriff, Tingting Tang, Robin Thompson, William
                    Waites
                    <br>
                    >>> Date submitted: 12 Oct 2021 <br>
                    >>> Edited by: Shayn Peirce-Cottler<br>
                    >>> <br>
                    >>> <br>
                    >>> Research Topic: Insights in Systems
                    Biology: Multiscale Mechanistic Modeling 2021<br>
                    >>> Review forum direct access link: <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Freview.frontiersin.org%2Freview%2F793932%2F0%2F0&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=%2B9EkL0eiqOgAgLYJqAVNr%2FM5vaTJvVEqzjjQBqF7RwA%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Freview.frontiersin.org%2Freview%2F793932%2F0%2F0&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=%2B9EkL0eiqOgAgLYJqAVNr%2FM5vaTJvVEqzjjQBqF7RwA%3D&amp;reserved=0</a><br>
                    >>> <br>
                    >>>
                    _______________________________________________<br>
                    >>> Vp-integration-subgroup mailing list<br>
                    >>> <a
                      href="mailto:Vp-integration-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">Vp-integration-subgroup@lists.simtk.org</a><br>
                    >>> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-integration-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=O96p1kQNUebcRbGUf7%2BCUYUf2Im%2FszHFAtpx0EJSAeQ%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-integration-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=O96p1kQNUebcRbGUf7%2BCUYUf2Im%2FszHFAtpx0EJSAeQ%3D&amp;reserved=0</a><br>
                    >>> <br>
                    >>> <br>
                    >>> -- <br>
                    >>> <br>
                    >>> Alexander Kulesza<br>
                    >>> <br>
                    >>> Team leader<br>
                    >>> <br>
                    >>> Modeling & simulation / Biomodeling<br>
                    >>> <br>
                    >>> <a
                      href="mailto:alexander.kulesza@novadiscovery.com"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">alexander.kulesza@novadiscovery.com</a><br>
                    >>> <br>
                    >>> +33 7 82 92 44 62<br>
                    >>> <br>
                    >>> nova<br>
                    >>> DISCOVERY<br>
                    >>> <br>
                    >>> <a
href="https://nam04.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.novadiscovery.com%2F&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=GoPLLBrztwRooALgnsK5CIKdgS8cq179j7SWSGirsEY%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.novadiscovery.com%2F&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=GoPLLBrztwRooALgnsK5CIKdgS8cq179j7SWSGirsEY%3D&amp;reserved=0</a><br>
                    >>> <br>
                    >>> 1 Place Verrazzano, 69009 Lyon +33 9 72
                    53 13 01<br>
                    >>> <br>
                    >>> <br>
                    >>> This message is intended only for the
                    personal and confidential use of the designated
                    recipient(s) named above. If you are not the
                    intended recipient of this message you are hereby
                    notified that any review, dissemination,
                    distribution or copying of this message is strictly
                    prohibited. Email transmission cannot be guaranteed
                    to be secure or error-free. Therefore, we do not
                    represent that this information is complete or
                    accurate and it should not be relied upon as such.
                    All information is subject to change without notice.<br>
                    >>>
                    _______________________________________________<br>
                    >>> Vp-integration-subgroup mailing list<br>
                    >>> <a
                      href="mailto:Vp-integration-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">Vp-integration-subgroup@lists.simtk.org</a><br>
                    >>> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-integration-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=O96p1kQNUebcRbGUf7%2BCUYUf2Im%2FszHFAtpx0EJSAeQ%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-integration-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=O96p1kQNUebcRbGUf7%2BCUYUf2Im%2FszHFAtpx0EJSAeQ%3D&amp;reserved=0</a><br>
                    >> <br>
                    >>
                    _______________________________________________<br>
                    >> Vp-reproduce-subgroup mailing list<br>
                    >> <a
                      href="mailto:Vp-reproduce-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">Vp-reproduce-subgroup@lists.simtk.org</a><br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-reproduce-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=7fBtOAwIBTjpZrcPej9zhJSJw1w1R8wTayRXqESDyqo%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-reproduce-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=7fBtOAwIBTjpZrcPej9zhJSJw1w1R8wTayRXqESDyqo%3D&amp;reserved=0</a><br>
                    >>
                    _______________________________________________<br>
                    >> Vp-reproduce-subgroup mailing list<br>
                    >> <a
                      href="mailto:Vp-reproduce-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">Vp-reproduce-subgroup@lists.simtk.org</a><br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-reproduce-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=7fBtOAwIBTjpZrcPej9zhJSJw1w1R8wTayRXqESDyqo%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-reproduce-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=7fBtOAwIBTjpZrcPej9zhJSJw1w1R8wTayRXqESDyqo%3D&amp;reserved=0</a><br>
                    >> <br>
                    >> <br>
                    >>
                    _______________________________________________<br>
                    >> Vp-reproduce-subgroup mailing list<br>
                    >> <br>
                    >> <a
                      href="mailto:Vp-reproduce-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">Vp-reproduce-subgroup@lists.simtk.org</a><br>
                    >> <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-reproduce-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=7fBtOAwIBTjpZrcPej9zhJSJw1w1R8wTayRXqESDyqo%3D&amp;reserved=0"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-reproduce-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=7fBtOAwIBTjpZrcPej9zhJSJw1w1R8wTayRXqESDyqo%3D&amp;reserved=0</a><br>
                    > -- <br>
                    > James A. Glazier, PhD<br>
                    > Professor of Intelligent Systems Engineering,
                    Adjunct Professor of Physics<br>
                    > Director, Biocomplexity Institute<br>
                    > Indiana University, Bloomington<br>
                    > (812) 391-2159 (cell)<br>
                    > <br>
                    > _______________________________________________<br>
                    > Vp-integration-subgroup mailing list<br>
                    > <a
                      href="mailto:Vp-integration-subgroup@lists.simtk.org"
                      target="_blank" moz-do-not-send="true"
                      class="moz-txt-link-freetext">Vp-integration-subgroup@lists.simtk.org</a><br>
                    > <a
href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-integration-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CU"
                      target="_blank" moz-do-not-send="true">
https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.simtk.org%2Fmailman%2Flistinfo%2Fvp-integration-subgroup&amp;data=04%7C01%7CWinston.Garira%40univen.ac.za%7C4afdd5cc058a498bc11008d9a1da2418%7Cf38ba9d8554c48a2ae4213b1e7f3c797%7C0%7C0%7C637718780727692287%7CU</a>nknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=O96p1kQNUebcRbGUf7%2BCUYUf2Im%2FszHFAtpx0EJSAeQ%3D&amp;reserved=0<br>
                    <br>
                  </div>
                </span></font></div>
          </div>
          _______________________________________________<br>
          Vp-integration-subgroup mailing list<br>
          <a href="mailto:Vp-integration-subgroup@lists.simtk.org"
            target="_blank" moz-do-not-send="true"
            class="moz-txt-link-freetext">Vp-integration-subgroup@lists.simtk.org</a><br>
          <a
            href="https://lists.simtk.org/mailman/listinfo/vp-integration-subgroup"
            rel="noreferrer" target="_blank" moz-do-not-send="true"
            class="moz-txt-link-freetext">https://lists.simtk.org/mailman/listinfo/vp-integration-subgroup</a><br>
        </blockquote>
      </div>
      <br clear="all">
      <div><br>
      </div>
      -- <br>
      <div dir="ltr" class="gmail_signature">
        <div dir="ltr">-- ------------------ 
          <div>Yaling Liu, Professor </div>
          <div>Department of Bioengineering, Director of Graduate
            Studies<br>
          </div>
          <div>Department of Mechanical Engineering and Mechanics </div>
          <div>Lehigh University </div>
          <div><a href="http://www.lehigh.edu/~yal310" target="_blank"
              moz-do-not-send="true">www.lehigh.edu/~yal310</a><br>
          </div>
        </div>
      </div>
    </blockquote>
    <pre class="moz-signature" cols="72">-- 
James A. Glazier, PhD
Professor of Intelligent Systems Engineering, Adjunct Professor of Physics
Director, Biocomplexity Institute
Indiana University, Bloomington
(812) 391-2159 (cell)</pre>
  </body>
</html>