[Population Modeling] Intro

[Uni HL]

Dear all,

Thank you very much for the invitation.

The Institute of Medical Biometry and Statistics at the University of Lubeck, Germany, is part of the "Biomarker for Cardiovascular Risk Assessment in Europe“ project, BiomarCaRE in brief. Although biomarkers are considered as tools to enhance cardiovascular risk estimation, the value of biomarkers on risk estimation beyond standard risk scores remains unclear. Their comparative impact among different European regions and their role towards personalized medicine also remains to be elucidated. In BiomarCaRE we aim at assessing the value of established and emerging biomarkers for cardiovascular risk prediction using standard statistical approaches as well as machine learning methods, such as random forests or support vector machines. The strength of BiomarCaRE lies in its well-defined primary and secondary prevention cohorts including over 300,000 participants from 13 European countries. 

Link to a recent publication describing the rationale and design of BiomarCaRE: http://www.ncbi.nlm.nih.gov/pubmed/25238720

Andreas Ziegler